This report presents the bioeconomy policy briefs developed in the context of the BIO4Africa project and led by AATF. As bio-based technologies are rolled out and as Africa increasingly builds its bioeconomy base, it is critical to establish an enabling environment composed of policies, strategies, regulations, guidelines, and standards that will facilitate the development, deployment and adoption of bioeconomy technologies, techniques, and practices. The policy environment is critical to create sufficient incentives for the emergence and sustaining of markets and value chains that are critical to enhance the development of a sustainable bioeconomy. The policy briefs presented in this report capture the key challenges that hinder the development of the bioeconomy. The report further suggests policy options for prioritization towards addressing these challenges. Separate from this report, four policy briefs have been developed, one for each country and will be used for individual country advocacy and policy engagement.